https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30266 Stenotrophomonas (MTS-2) followed by Citrobacter (MTS-3) and Pseudomonas (MTS-1) were furthermost effective in the degradation of HMW PAHs either as individual or in the presence of co-substrate (LMW PAHs). MTS-1, 2 and 3 (co)degraded model LMW PAHs, Phe (100% of 150 mg L^-1) and HMW PAHs Pyr (100% of 150 mg L^-1) or BaP (90-100% of 50 mg L^-1) in 3, 12-15 and 30 days, respectively and recorded the least half-life time (t^1/2) and highest biodegradation rate constants (k). One of the significant findings is the diazotrophic P-solubilization ability, acid and alkali tolerance (optimum pH=5.0-8.0) of the HMW PAHs degrading Pseudomonas strain MTS-1. Stenotrophomonas (MTS-2) was also found to be superior as it could solubilize P and tolerate acidic condition (optimum pH=5.0-7.5) during HMW PAHs degradation. Further, our study is the first evidence of diazotrophic P solubilization potential of Agrobacterium (MTS-4) and P-solubilizing capacity of Citrobacter (MTS-3) during bioremediation. Thus, the results of this study demonstrate the promising use of the newly identified PAH degraders, notably MTS-1, 2 and 3 either as individuals or as consortia as an excellent candidate in the bioremediation or phytoremediation of PAHs contaminated soils.]]> Wed 04 Sep 2019 10:24:28 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30320 rat = 0.26RB_swine + 17.3, R2 = 0.70, p < 0.001), despite the regression slope coefficient revealing that the rat model would underestimate RB by about one quarter compared to using swine. Conclusions: In the comparison employed in this study, an interspecies difference of four in RB using AUC assay was identified between the rat and swine models regarding pharmacokinetic differences, which supported the body weight scaling method recommended by US EPA. Future research should focus on the carcinogenic competency (pharmacodynamics) used in experiment animals and humans.]]> Sat 24 Mar 2018 07:31:49 AEDT ]]>